1
: not made use of, won, or claimed
a lost opportunity
2
a
: no longer possessed
a lost reputation
b
: no longer known
a lost tunnel
3
: ruined or destroyed physically or morally : desperate
a lost soul
4
a
: taken away or beyond reach or attainment : denied
regions lost to the faith
b
: insensible, hardened
lost to shame
5
a
: unable to find the way
b
: no longer visible
lost in the crowd
c
: lacking assurance or self-confidence : helpless
lost without his glasses
7
: not appreciated or understood : wasted
Their jokes were lost on me.
8
: obscured or overlooked during a process or activity
lost in translation
9
: hopelessly unattainable : futile
a lost cause
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Merriam-Webster unabridged
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